Cell Immortalization: In Vivo Molecular Bases and In Vitro Techniques for Obtention
Somatic human cells can divide a finite number of times, a phenomenon known as the Hayflick limit.It is based on the progressive erosion of the telomeric ends each time the cell completes a replicative cycle.Given this abc material problem, researchers need cell lines that do not enter the senescence phase after a certain number of divisions.In thi